Exhausted Kevin Anderson called for Grand Slam chiefs to introduce a cut-off point for final set marathons after the South African reached the Wimbledon final by winning the second longest ever singles match at a major.
Fast food chain Nandos, which originated from South Africa, has pledged to give away free meals to people who share names with the two players, until Anderson is knocked out of the tournament or wins the final.
This time, however, Isner came out on the losing end, falling 7-6 (6), 6-7 (5), 6-7 (9), 6-4, 26-24 in six hours, 35 minutes on Centre Court.
It was the longest semi-final ever played at Wimbledon, surpassing the four hours 44 minutes it took Djokovic to beat Juan Martin del Potro in 2013.
Only one match at the All England Club has been longer: Isner's record-setting 2010 first-round victory over Nicolas Mahut, which went more than 11 hours over three days and finished 70-68 in the fifth.
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After beating eight-time champion Roger Federer, also over five sets in the quarter-finals, 2017 US Open runner-up Anderson claimed his 300th career win.
Paulina Dedaj is a writer/ reporter for Fox News.
That service hold - helped by a 129 miles per hour (207.6km/h) second serve - took the American to 100 service games unbroken at this Wimbledon.
Again, the pair traded breaks early in the fourth, but Anderson broke and eventually served it out to take the match into a decider after three hours and 40 minutes.
Raonic delivered what was expected of him, smashing 31 aces to Isner's 25 in a booming encounter, but a failure to convert a set point in the second set tiebreak proved crucial.
Isner was famously apart of the longest match in tennis history.