Pogba missed Saturday's 2-0 FA Cup win at Huddersfield because he was unwell but had been expected to return to the first XI in Seville.
"I only see a club like Real Madrid or Barcelona, with Ronaldo or Messi on their best days, scoring five or six goals here", Mourinho said.
De Gea (27), signed for the Red Devils in 2011 and after a shaky start managed to cure United's immediate goalkeeper problems after Edwin van de Sar hung up his gloves that very same year.
But fate intervened and he came on to replace the injured Ander Herrera after just 16 minutes, producing a dynamic, hardworking midfield display. "For a match away to Sevilla we had a good percentage of the ball, and I think Paul had responsibility for that".
Had United emulated mid-noughties era Chelsea, or early 2010s Inter, and restricted their opponents to non-threatening, speculative efforts then perhaps we would be celebrating Mourinho's tactical astuteness. He was unable to engineer many attacks and sent a long, hopeful shot well wide of goal in the second half.
"Once you're out there, you just forget about it - it's a game of football on a pitch that you've played on before, so, you just take it from there, want to play your game and that is it". "I thought it was a good performance from the whole team, everybody played well and that's the main thing going back to Old Trafford".
Microsoft co-founder Bill Gates has no idea what groceries cost
Bill was way off the mark on most of his guesses apart from dental floss which he was just a few cents away from the actual price. He thought a $20 container of Tide Pods cost $4 and gave a wildly exorbitant guess at the cost of a bag of Totino's Pizza Rolls .
"The only moment where we felt relieved was in the last couple of moments of the first half when from a couple of our mistakes in possession they had a couple of good situations and De Gea made good saves", said Mourinho. "I made a save and I'm happy for that".
"Of course last season we had the Europa League, but that has a different meaning".
United's latest high-profile signing, Alexis Sanchez, also had a night to forget in his first European game for the club since joining from Arsenal in January as he saw little of the ball and was hauled off for Marcus Rashford in the 75th minute.
Wright damningly concluded: "The United teams of old, especially the ones that I played against, it was all about pace and getting forward quickly, and passing quickly".
The Serie A team appeared to be coasting in the round of 16 first leg tie when Cengiz Under put them ahead with his fifth goal in four games four minutes before half-time.